Bioquímica e Biologia Humana

Principais Atividades

Ensino de 1.º, 2.º e 3.º ciclos.
Investigação científica e desenvolvimento tecnológico.
Serviços de extensão universitária:
            serviços ao exterior
            atividades complementares no domínio da formação contínua e da promoção da inovação.

Órgãos

Presidente
Maria da Graça Tavares Rebelo de Soveral Rodrigues

Comissão Executiva
Ana Paula Costa Santos Peralta Leandro (Recursos Financeiros)
Isabel Maria Antolin Rivera (Serviço Docente e Qualidade Pedagógica)
Maria João Carlos Silva Gama (Recursos Humanos e Segurança)
Rui Fernando Marques da Silva (Recursos e Estruturas)

Ensino

O DBBH está ativamente envolvido na lecionação de vários cursos da FFUL e também de alguns cursos em associação com Escolas da ULisboa ou outras instituições de ensino superior.

Anatomia Humana
Biologia Celular
Biologia Molecular
Bioinformática
Bioquímica I
Bioquímica II
Bioquímica Clínica
Bioquímica Clínica Analítica
Engenharia Genética
Genética Humana
Genética Molecular Experimental
Hematologia
Histologia e Embriologia
Introdução à Neurobiologia
Laboratório de Biologia
Nutrição e Dietética

Especialidades de Biologia Celular e Molecular, de Bioquímica, de Biotecnologia Farmacêutica e Toxicologia.

Programa Doutoral em Medicamento e Inovação Farmacêutica (i3DU)

Licenciatura
Ciências da Saúde (ciclo de estudos em associação)

Mestrado Integrado
Mestrado Integrado em Engenharia Biomédica e Biofísica da Faculdade de Ciências da ULisboa
Mestrado em Biologia Molecular e Genética da Faculdade de Ciências da ULisboa

Programas Doutorais
Programa Doutoral em Bioquímica e Biofísica Médica (M2B-PhD)
Programa Doutoral em Microsistemas Integrados Avançados (AIM)
Programa Doutoral em Neurociências Integradas (NeurULisboa)
Programa Doutoral em Química Medicinal (MedChemTrain)

Cursos Não Conferentes de Grau
Curso Avançado Biomarkers and Assay Development, 14-18 de setembro de 2015
XX Curso de pós-graduação e atualização em Hematologia – 2.ª edição. Patologia Leucocitária, 21 e 22 de fevereiro de 2015
XX Curso de pós-graduação e atualização em Hematologia – 3.ª edição. Patologia Leucocitária, 20 e 21 de junho de 2015
XXI Curso de pós-graduação e atualização em Hematologia – 1.ª edição. Patologia dos eritrócitos: Anemias, poliglobulias e hemocromatoses. 11 e 12 de abril de 2015
XXII Curso de pós-graduação e atualização em Hematologia – 1.ª edição. Anemias hemolíticas, 31 de outubro e 1 de novembro de 2015

Investigação

Instituto de Investigação do Medicamento (iMed.ULisboa)

            Grupos de Investigação:
            Biologia Neuro-Glial na Saúde e na Doença
            Função Celular e Alvos Terapêuticos
            Metabolismo e Genética

2017

AnoTítuloAutor(es)Tipo de Documento
2017Morte celular no sistema nervoso

Livros e Capítulos de Livros

Ref.: Nunes A, Ramalho R, Rodrigues CMP. Morte celular no sistema nervoso. In: Rego AC, Duarte CB, Oliveira CR, editors. Neurociências. Lisboa: Lidel; 2017. p. 499–512.
2017Vicente JB, Colaço HG, Malagrinò F, Santo PE, Gutierres A, Bandeiras TM, et al. A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β -Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity? Oxidative Medicine and Cellular Longevity. 2017;2017

Artigos

Ref.: Vicente JB, Colaço HG, Malagrinò F, Santo PE, Gutierres A, Bandeiras TM, et al. A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β -Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity? Oxidative Medicine and Cellular Longevity. 2017;2017
2017Vale FF, Nunes A, Oleastro M, Gomes JP, Sampaio DA, Rocha R, et al. Genomic structure and insertion sites of Helicobacter pylori prophages from various geographical origins. Scientific Reports. 2017;7

Artigos

Ref.: Vale FF, Nunes A, Oleastro M, Gomes JP, Sampaio DA, Rocha R, et al. Genomic structure and insertion sites of Helicobacter pylori prophages from various geographical origins. Scientific Reports. 2017;7
2017Thorell K, Lehours P, Vale FF. Genomics of Helicobacter pylori. Helicobacter. 2017;22

Artigos

Ref.: Thorell K, Lehours P, Vale FF. Genomics of Helicobacter pylori. Helicobacter. 2017;22
2017Tenreiro MM, Correia ML, Brito MA. Endothelial progenitor cells in multiple myeloma neovascularization: a brick to the wall. Angiogenesis. 2017;20(4):443–62

Artigos

Ref.: Tenreiro MM, Correia ML, Brito MA. Endothelial progenitor cells in multiple myeloma neovascularization: a brick to the wall. Angiogenesis. 2017;20(4):443–62
2017Soveral G, Casini A. Aquaporin modulators: a patent review (2010–2015). Expert Opinion on Therapeutic Patents. 2017;27(1):49–62

Artigos

Ref.: Soveral G, Casini A. Aquaporin modulators: a patent review (2010–2015). Expert Opinion on Therapeutic Patents. 2017;27(1):49–62
2017Silva B, Nunes A, Vale FF, Rocha R, Gomes JP, Dias R, et al. The expression of Helicobacter pylori tfs plasticity zone cluster is regulated by pH and adherence, and its composition is associated with differential gastric IL-8 secretion. Helicobacter. 2017;22(4)

Artigos

Ref.: Silva B, Nunes A, Vale FF, Rocha R, Gomes JP, Dias R, et al. The expression of Helicobacter pylori tfs plasticity zone cluster is regulated by pH and adherence, and its composition is associated with differential gastric IL-8 secretion. Helicobacter. 2017;22(4)
2017Santos T, Ferreira R, Quartin E, Boto C, Saraiva C, Bragança J, et al. Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles. Acta Biomaterialia. 2017;59:293–302

Artigos

Ref.: Santos T, Ferreira R, Quartin E, Boto C, Saraiva C, Bragança J, et al. Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles. Acta Biomaterialia. 2017;59:293–302
2017Rosa AI, Fonseca I, Nunes MJ, Moreira S, Rodrigues E, Carvalho AN, et al. Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson’s disease. Biochimica et Biophysica Acta – Molecular Basis of Disease. 2017;1863(9):2171–81

Artigos

Ref.: Rosa AI, Fonseca I, Nunes MJ, Moreira S, Rodrigues E, Carvalho AN, et al. Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson’s disease. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2017;1863(9):2171–81
2017Rodrigues PM, Afonso MB, Simaõ AL, Carvalho CC, Trindade A, Duarte A, et al. MiR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice. Cell Death and Disease. 2017;8(4)

Artigos

Ref.: Rodrigues PM, Afonso MB, Simaõ AL, Carvalho CC, Trindade A, Duarte A, et al. MiR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice. Cell Death and Disease. 2017;8(4)
2017Rodrigues C, Tartaro Bujak I, Mihaljević B, Soveral G, Cipak Gasparovic A. Yeast aquaporin regulation by 4-hydroxynonenal is implicated in oxidative stress response. IUBMB Life. 2017;69(5):355–62

Artigos

Ref.: Rodrigues C, Tartaro Bujak I, Mihaljević B, Soveral G, Cipak Gasparovic A. Yeast aquaporin regulation by 4-hydroxynonenal is implicated in oxidative stress response. IUBMB Life. 2017;69(5):355–62
2017Ribeiro CJA, Nunes RC, Amaral JD, Gonçalves LM, Rodrigues CMP, Moreira R, et al. Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties. European Journal of Medicinal Chemistry. 2017;140:494–509

Artigos

Ref.: Ribeiro CJA, Nunes RC, Amaral JD, Gonçalves LM, Rodrigues CMP, Moreira R, et al. Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties. European Journal of Medicinal Chemistry. 2017;140:494–509
2017Reis-Pardal J, Rodrigues A, Rodrigues E, Fernandez-Llimos F. Comparing cytochrome P450 pharmacogenetic information available on United States drug labels and European Union Summaries of Product Characteristics. Pharmacogenomics Journal. 2017;17(6):488–93

Artigos

Ref.: Reis-Pardal J, Rodrigues A, Rodrigues E, Fernandez-Llimos F. Comparing cytochrome P450 pharmacogenetic information available on United States drug labels and European Union Summaries of Product Characteristics. Pharmacogenomics Journal. 2017;17(6):488–93
2017Raaf N, Amhis W, Saoula H, Abid A, Nakmouche M, Balamane A, et al. Prevalence, antibiotic resistance, and MLST typing of Helicobacter pylori in Algiers, Algeria. Helicobacter. 2017;22(6)

Artigos

Ref.: Raaf N, Amhis W, Saoula H, Abid A, Nakmouche M, Balamane A, et al. Prevalence, antibiotic resistance, and MLST typing of Helicobacter pylori in Algiers, Algeria. Helicobacter. 2017;22(6)
2017Pinto S, Cunha C, Barbosa M, Vaz AR, Brites D. Exosomes from NSC-34 cells transfected with hSOD1-G93A are enriched in mir-124 and drive alterations in microglia phenotype. Frontiers in Neuroscience. 2017;11(MAY)

Artigos

Ref.: Pinto S, Cunha C, Barbosa M, Vaz AR, Brites D. Exosomes from NSC-34 cells transfected with hSOD1-G93A are enriched in mir-124 and drive alterations in microglia phenotype. Frontiers in Neuroscience. 2017;11(MAY)
2017Pinheiro R, Braga C, Santos G, Bronze MR, Perry MJ, Moreira R, et al. Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference? ACS Chemical Neuroscience. 2017;8(1):50–9

Artigos

Ref.: Pinheiro R, Braga C, Santos G, Bronze MR, Perry MJ, Moreira R, et al. Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference? ACS Chemical Neuroscience. 2017;8(1):50–9
2017Oleastro M, Rocha R, Vale FF. Population genetic structure of Helicobacter pylori strains from Portuguese-speaking countries. Helicobacter. 2017;22(4)

Artigos

Ref.: Oleastro M, Rocha R, Vale FF. Population genetic structure of Helicobacter pylori strains from Portuguese-speaking countries. Helicobacter. 2017;22(4)
2017Nunes RC, Ribeiro CJA, Monteiro Â, Rodrigues CMP, Amaral JD, Santos MMM. In vitro targeting of colon cancer cells using spiropyrazoline oxindoles. European Journal of Medicinal Chemistry. 2017;139:168–79

Artigos

Ref.: Nunes RC, Ribeiro CJA, Monteiro Â, Rodrigues CMP, Amaral JD, Santos MMM. In vitro targeting of colon cancer cells using spiropyrazoline oxindoles. European Journal of Medicinal Chemistry. 2017;139:168–79
2017Moutinho M, Nunes MJ, Rodrigues E. The mevalonate pathway in neurons: It’s not just about cholesterol. Experimental Cell Research. 2017;360(1):55–60

Artigos

Ref.: Moutinho M, Nunes MJ, Rodrigues E. The mevalonate pathway in neurons: It’s not just about cholesterol. Experimental Cell Research. 2017;360(1):55–60
2017Morris AAM, Kozich V, Santra S, Andria G, Ben-Omran TIM, Chakrapani AB, et al. Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency. Journal of Inherited Metabolic Disease. 2017 Jan;40(1):49–74

Artigos

Ref.: Morris AAM, Kozich V, Santra S, Andria G, Ben-Omran TIM, Chakrapani AB, et al. Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency. Journal of Inherited Metabolic Disease. 2017 Jan;40(1):49–74
2017Moreira S, Fonseca I, Nunes MJ, Rosa A, Lemos L, Rodrigues E, et al. Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson’s disease. Experimental Neurology. 2017;295:77–87

Artigos

Ref.: Moreira S, Fonseca I, Nunes MJ, Rosa A, Lemos L, Rodrigues E, et al. Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson’s disease. Experimental Neurology. 2017;295:77–87
2017Moedas MF, Adam AAA, Farelo MA, IJlst L, Chamuleau RAFM, Hoekstra R, et al. Advances in methods for characterization of hepatic urea cycle enzymatic activity in HepaRG cells using UPLC-MS/MS. Analytical Biochemistry. 2017;535:47–55

Artigos

Ref.: Moedas MF, Adam AAA, Farelo MA, IJlst L, Chamuleau RAFM, Hoekstra R, et al. Advances in methods for characterization of hepatic urea cycle enzymatic activity in HepaRG cells using UPLC-MS/MS. Analytical Biochemistry. 2017;535:47–55
2017Méndez-Giménez L, Becerril S, Moncada R, Valentí V, Fernández S, Ramírez B, et al. Gastric Plication Improves Glycemia Partly by Restoring the Altered Expression of Aquaglyceroporins in Adipose Tissue and the Liver in Obese Rats. Obesity Surgery. 2017;27(7):1763–74

Artigos

Ref.: Méndez-Giménez L, Becerril S, Moncada R, Valentí V, Fernández S, Ramírez B, et al. Gastric Plication Improves Glycemia Partly by Restoring the Altered Expression of Aquaglyceroporins in Adipose Tissue and the Liver in Obese Rats. Obesity Surgery. 2017;27(7):1763–74
2017Méndez-Giménez L, Becerril S, Camões SP, Da Silva IV, Rodrigues C, Moncada R, et al. Role of aquaporin-7 in ghrelin-and GLP-1-induced improvement of pancreatic β-cell function after sleeve gastrectomy in obese rats. International Journal of Obesity. 2017;41(9):1394–402

Artigos

Ref.: Méndez-Giménez L, Becerril S, Camões SP, Da Silva IV, Rodrigues C, Moncada R, et al. Role of aquaporin-7 in ghrelin-and GLP-1-induced improvement of pancreatic β-cell function after sleeve gastrectomy in obese rats. International Journal of Obesity. 2017;41(9):1394–402
2017Martins SV, Pires VMR, Madeira AP, Nascimento M, Alfaia CM, Castro MF, et al. Novel anti-adipogenic properties of the individual trans8,cis10 conjugated linoleic acid (CLA) isomer in 3T3-L1 adipocytes. European Journal of Lipid Science and Technology. 2017;119(2)

Artigos

Ref.: Martins SV, Pires VMR, Madeira AP, Nascimento M, Alfaia CM, Castro MF, et al. Novel anti-adipogenic properties of the individual trans8,cis10 conjugated linoleic acid (CLA) isomer in 3T3-L1 adipocytes. European Journal of Lipid Science and Technology. 2017;119(2)

2016

AnoTítuloAutor(es)Tipo de Documento
2016Carvalho AN, Firuzi O, Gama MJ, van Horssen J, Saso L. Oxidative stress and antioxidants in neurological diseases: Is there still hope? Current Drug Targets. 2016;17(16).

Artigos

Ref.: Carvalho AN, Firuzi O, Gama MJ, van Horssen J, Saso L. Oxidative stress and antioxidants in neurological diseases: Is there still hope? Current Drug Targets. 2016;17(16).
2016Vaz A, Gomes C, Cunha C, Brites D. Astrocytes in Amyotrophic Lateral Sclerosis: Harmful Effects and Strategies to Afford Neuroprotection. In: New Developments in Astrocytes Research. New York: Nova Science Publishers; 2016. p. 67–111.

Livros e Capítulos de Livros

Ref.: Vaz A, Gomes C, Cunha C, Brites D. Astrocytes in Amyotrophic Lateral Sclerosis: Harmful Effects and Strategies to Afford Neuroprotection. In: New Developments in Astrocytes Research. New York: Nova Science Publishers; 2016. p. 67–111.
2016Ribeiro CJA, Amaral JD, Rodrigues CMP, Moreira R, Santos MMM. Spirooxadiazoline oxindoles with promising in vitro antitumor activities. MedChemComm. 2016;7(3):420–5.

Artigos

Ref.: Ribeiro CJA, Amaral JD, Rodrigues CMP, Moreira R, Santos MMM. Spirooxadiazoline oxindoles with promising in vitro antitumor activities. MedChemComm. 2016;7(3):420–5.
2016Simões AES, Rodrigues CMP, Borralho PM. The MEK5/ERK5 signalling pathway in cancer: a promising novel therapeutic target. Drug Discovery Today. 2016;21(10):1654–63.

Artigos

Ref.: Simões AES, Rodrigues CMP, Borralho PM. The MEK5/ERK5 signalling pathway in cancer: a promising novel therapeutic target. Drug Discovery Today. 2016;21(10):1654–63.
2016von Zglinicki T, Varela Nieto I, Brites D, Karagianni N, Ortolano S, Georgopoulos S, et al. Frailty in mouse ageing: A conceptual approach. Mechanisms of Ageing and Development. 2016;160:34–40.

Artigos

Ref.: von Zglinicki T, Varela Nieto I, Brites D, Karagianni N, Ortolano S, Georgopoulos S, et al. Frailty in mouse ageing: A conceptual approach. Mechanisms of Ageing and Development. 2016;160:34–40.
2016Pereira R, Mesquita P, Matos J, Baptista M, Silva E, Horta A, et al. Effect of P2Y2 receptors modulation on bovine oocyte cryosurvival. Reproduction in Domestic Animals. 2016;51(2, SI):129.

Outras Publicações Indexadas

Ref.: Pereira R, Mesquita P, Matos J, Baptista M, Silva E, Horta A, et al. Effect of P2Y2 receptors modulation on bovine oocyte cryosurvival. Reproduction in Domestic Animals. 2016;51(2, SI):129.
2016Ribeiro FF, Neves-Tomé R, Assaife-Lopes N, Santos TE, Silva RFM, Brites D, et al. Axonal elongation and dendritic branching is enhanced by adenosine Areceptors activation in cerebral cortical neurons. Brain Structure and Function. 2016;221(5):2777–99.

Artigos

Ref.: Ribeiro FF, Neves-Tomé R, Assaife-Lopes N, Santos TE, Silva RFM, Brites D, et al. Axonal elongation and dendritic branching is enhanced by adenosine A2Areceptors activation in cerebral cortical neurons. Brain Structure and Function. 2016;221(5):2777–99.
2016Tenreiro MM, Ferreira R, Bernardino L, Brito MA. Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration. Neurobiology of Disease. 2016 Jul;91:262–73.

Artigos

Ref.: Tenreiro MM, Ferreira R, Bernardino L, Brito MA. Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration. Neurobiology of Disease. 2016 Jul;91:262–73.
2016Vicente JB, Colaço HG, Sarti P, Leandro P, Giuffrè A. S-adenosyl-L-methionine modulates CO and NO· binding to the human H2S-generating enzyme cystathionine β-synthase. Journal of Biological Chemistry. 2016;291(2):572–81.

Artigos

Ref.: Vicente JB, Colaço HG, Sarti P, Leandro P, Giuffrè A. S-adenosyl-L-methionine modulates CO and NO· binding to the human H2S-generating enzyme cystathionine β-synthase. Journal of Biological Chemistry. 2016;291(2):572–81.
2016Marques C, Santos-Silva C, Rodrigues C, Matos J, Moura T, Baptista MC, et al. Effect of different cocktails of cryoprotectants and calcium on bovine oocyte membrane permeability and cryosurvival. Reproduction In Domestic Animals. 2016;51(2, SI):114.

Outras Publicações Indexadas

Ref.: Marques C, Santos-Silva C, Rodrigues C, Matos J, Moura T, Baptista MC, et al. Effect of different cocktails of cryoprotectants and calcium on bovine oocyte membrane permeability and cryosurvival. Reproduction In Domestic Animals. 2016;51(2, SI):114.
2016Rodrigues C, Mósca AF, Martins AP, Nobre T, Prista C, Antunes F, et al. Rat aquaporin-5 is pH-gated induced by phosphorylation and is implicated in oxidative stress. International Journal of Molecular Sciences. 2016;17(12).

Artigos

Ref.: Rodrigues C, Mósca AF, Martins AP, Nobre T, Prista C, Antunes F, et al. Rat aquaporin-5 is pH-gated induced by phosphorylation and is implicated in oxidative stress. International Journal of Molecular Sciences. 2016;17(12).
2016Xavier JM, Rodrigues CMP, Solá S. Mitochondria: Major Regulators of Neural Development. Neuroscientist. 2016;22(4):346–58.

Artigos

Ref.: Xavier JM, Rodrigues CMP, Solá S. Mitochondria: Major Regulators of Neural Development. Neuroscientist. 2016;22(4):346–58.
2016Paterna A, Gomes SE, Borralho PM, Mulhovo S, Rodrigues CMP, Ferreira M-JU. Vobasinyl-Iboga Alkaloids from Tabernaemontana elegans: Cell Cycle Arrest and Apoptosis-Inducing Activity in HCT116 Colon Cancer Cells. Journal of Natural Products. 2016;79(10):2624–34.

Artigos

Ref.: Paterna A, Gomes SE, Borralho PM, Mulhovo S, Rodrigues CMP, Ferreira M-JU. Vobasinyl-Iboga Alkaloids from Tabernaemontana elegans: Cell Cycle Arrest and Apoptosis-Inducing Activity in HCT116 Colon Cancer Cells. Journal of Natural Products. 2016;79(10):2624–34.
2016Gomes SE, Simões AES, Pereira DM, Castro RE, Rodrigues CMP, Borralho PM. miR-143 or miR-145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells. Oncotarget. 2016;7(8):9368–87.

Artigos

Ref.: Gomes SE, Simões AES, Pereira DM, Castro RE, Rodrigues CMP, Borralho PM. miR-143 or miR-145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells. Oncotarget. 2016;7(8):9368–87.
2016Florindo PR, Pereira DM, Borralho PM, Costa PJ, Piedade MFM, Rodrigues CMP, et al. New [(η5-C5H5)Ru(N-N)(PPh3)][PF6]compounds: Colon anticancer activity and GLUT-mediated cellular uptake of carbohydrate-appended complexes. Dalton Transactions. 2016;45(30):11926–30.

Artigos

Ref.: Florindo PR, Pereira DM, Borralho PM, Costa PJ, Piedade MFM, Rodrigues CMP, et al. New [(η5-C5H5)Ru(N-N)(PPh3)][PF6]compounds: Colon anticancer activity and GLUT-mediated cellular uptake of carbohydrate-appended complexes. Dalton Transactions. 2016;45(30):11926–30.
2016Janota C, Lemere CA, Brito MA. Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer’s Disease. Molecular Neurobiology. 2016;53(6):3793–811.

Artigos

Ref.: Janota C, Lemere CA, Brito MA. Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer’s Disease. Molecular Neurobiology. 2016;53(6):3793–811.
2016Paterna A, Gomes SE, Borralho PM, Mulhovo S, Rodrigues CMP, Ferreira M-JU. (3′R)-hydroxytabernaelegantine C: A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells. Journal of Ethnopharmacology. 2016;194:236–44.

Artigos

Ref.: Paterna A, Gomes SE, Borralho PM, Mulhovo S, Rodrigues CMP, Ferreira M-JU. (3′R)-hydroxytabernaelegantine C: A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells. Journal of Ethnopharmacology. 2016;194:236–44.
2016Magalhaes A, Matias I, Palmela I, Brito MA, Dias S. LDL-cholesterol increases the transcytosis of molecules through endothelial monolayers. PLoS ONE. 2016;11(10).

Artigos

Ref.: Magalhaes A, Matias I, Palmela I, Brito MA, Dias S. LDL-cholesterol increases the transcytosis of molecules through endothelial monolayers. PLoS ONE. 2016;11(10).
2016Figueira M-E, Oliveira M, Direito R, Rocha J, Alves P, Serra A-T, et al. Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat. Biomedicine and Pharmacotherapy. 2016;83:1191–202.

Artigos

Ref.: Figueira M-E, Oliveira M, Direito R, Rocha J, Alves P, Serra A-T, et al. Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat. Biomedicine and Pharmacotherapy. 2016;83:1191–202.
2016Houten SM, Violante S, Ventura FV, Wanders RJA. The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders. Annual Review of Physiology. 2016;78:23-44.

Artigos

Ref.: Houten SM, Violante S, Ventura FV, Wanders RJA. The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders. Annual Review of Physiology. 2016;78:23-44.
2016Rodrigues CMP, Moshage H. Targeting TGR5 in cholangiocyte proliferation: Default topic. Gut. 2016;65(3):369–70.

Outras Publicações Indexadas

Ref.: Rodrigues CMP, Moshage H. Targeting TGR5 in cholangiocyte proliferation: Default topic. Gut. 2016;65(3):369–70.
2016Moedas MF, van Cruchten AG, IJlst L, Kulik W, de Almeida IT, Diogo L, et al. Transient decrease of hepatic NAD+and amino acid alterations during treatment with valproate: new insights on drug-induced effects in vivo using targeted MS-based metabolomics. Metabolomics. 2016;12(8).

Artigos

Ref.: Moedas MF, van Cruchten AG, IJlst L, Kulik W, de Almeida IT, Diogo L, et al. Transient decrease of hepatic NAD+and amino acid alterations during treatment with valproate: new insights on drug-induced effects in vivo using targeted MS-based metabolomics. Metabolomics. 2016;12(8).
2016Zarrouk O, Garcia-Tejero I, Pinto C, Genebra T, Sabir F, Prista C, et al. Aquaporins isoforms in cv. Touriga Nacional grapevine under water stress and recovery-Regulation of expression in leaves and roots. Agricultural Water Management. 2016 Jan;164(1, SI):167–75.

Artigos

Ref.: Zarrouk O, Garcia-Tejero I, Pinto C, Genebra T, Sabir F, Prista C, et al. Aquaporins isoforms in cv. Touriga Nacional grapevine under water stress and recovery-Regulation of expression in leaves and roots. Agricultural Water Management. 2016 Jan;164(1, SI):167–75.
2016Madeira A, Moura TF, Soveral G. Detecting aquaporin function and regulation. Frontiers in Chemistry. 2016;4(FEB).

Artigos

Ref.: Madeira A, Moura TF, Soveral G. Detecting aquaporin function and regulation. Frontiers in Chemistry. 2016;4(FEB).
2016Bonito CA, Nunes J, Leandro J, Louro F, Leandro P, Ventura FV, et al. Unveiling the Pathogenic Molecular Mechanisms of the Most Common Variant (p.K329E) in Medium-Chain Acyl-CoA Dehydrogenase Deficiency by in Vitro and in Silico Approaches. Biochemistry. 2016;55(51):7086–98.

Artigos

Ref.: Bonito CA, Nunes J, Leandro J, Louro F, Leandro P, Ventura FV, et al. Unveiling the Pathogenic Molecular Mechanisms of the Most Common Variant (p.K329E) in Medium-Chain Acyl-CoA Dehydrogenase Deficiency by in Vitro and in Silico Approaches. Biochemistry. 2016;55(51):7086–98.

Contactos

Localização: Edifício H - C.2.9
Tel.: +351 217 946 400
Extensão interna: 14345
E-mail: gsoveral@ff.ulisboa.pt

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