Farmácia Galénica e Tecnologia Farmacêutica

Principais Atividades

Ensino de 1.º, 2.º e 3.º ciclos.
Investigação científica e desenvolvimento tecnológico.
Serviços de extensão universitária:
            serviços ao exterior
            atividades complementares no domínio da formação contínua e da promoção da inovação.

Órgãos

Presidente
Helena Maria Cabral Marques

Comissão Executiva
António José Almeida
Helena Maria Cabral Marques
Helena Margarida Ribeiro
João Pinto
Maria Bárbara dos Anjos Figueira Martins

Comissão de Departamento
A Comissão de Departamento é constituída pelos Doutores do DFGTF com vínculo à FFUL.

Investigação

Instituto de Investigação do Medicamento (iMed.ULisboa)
           
Grupos de Investigação:
            BioNanoCiências – Transporte de Fármacos e Imunoterapia
            Sistemas Nanoestruturados para Superar Barreiras Biológicas

2019

2018

2017

  • Adeoye O, Cabral-Marques H. Cyclodextrin nanosystems in oral drug delivery: A mini review. International Journal of Pharmaceutics. 2017;531(2):521–31.
  • Adeoye O, Figueiredo A, Marques HC, Figueiredo A, Marques HC. Cyclodextrins and Skin Disorders: Therapeutic and Cosmetic Applications. In: Ascenso A, Ribeiro H, Simões S. Carrier-mediated dermal delivery : applications in the prevention and treatment of skin disorders. Singapore: Pan Stanford; 2017. p. 463-501
  • Afonso MB, Rodrigues PM, Simao AL, Gaspar MM, Castro RE, Rodrigues CMP. miRNA-21-deficiency reduces liver injury, fibrosis and necroptosis in cholestatic bile duct-ligated mice. Journal of Hepatology. 2017;66(1, S):S555.
  • Aguiar JP, Fernandes TAP, Nese C, Fernandes AI, Pinto JF. Production and characterization of spray-dried theophylline powders prepared from fresh milk for potential use in paediatrics. Journal of Pharmacy and Pharmacology. 2017;69(5):554–66.
  • Ascenso A, Ribeiro H, Simões S. Carrier-mediated dermal delivery : applications in the prevention and treatment of skin disorders. Singapore: Pan Stanford; 2017.
  • Baltazar D, Marto J, Berger T, Pinto P, Ribeiro HM. The antiageing efficacy of donkey milk in combination with pomegranate extract and UV protection A traditional ingredient in a modern formulation. Agro Food Industry Hi-Tech. 2017;28(2, SI):25–7.
  • Brereton RG, Jansen J, Lopes J, Marini F, Pomerantsev A, Rodionova O, et al. Chemometrics in analytical chemistry—part I: history, experimental design and data analysis tools. Analytical and Bioanalytical Chemistry. 2017;409(25):5891–9.
  • Bárcia RN, Santos JM, Teixeira M, Filipe M, Pereira ARS, Ministro A, et al. Umbilical cord tissue–derived mesenchymal stromal cells maintain immunomodulatory and angiogenic potencies after cryopreservation and subsequent thawing. Cytotherapy. 2017;19(3):360–70.
  • Caetano LA, Faria T, Batista AC, Viegas S, Viegas C. Assessment of occupational exposure to azole resistant fungi in 10 Portuguese bakeries. AIMS Microbiology. 2017;3(4):960–75.
  • Caetano LA, Figueiredo L, Almeida AJ, Gonçalves LMD. BCG-loaded chitosan microparticles: interaction with macrophages and preliminary in vivo studies. Journal of Microencapsulation. 2017;34(2):203–17.
  • Carreira AC, De Almeida RFM, Silva LC. Development of lysosome-mimicking vesicles to study the effect of abnormal accumulation of sphingosine on membrane properties. Scientific Reports. 2017;7(1).
  • Carvalho A, Goncalves MC, Corvo ML, Martins MBF. Development of New Contrast Agents for Imaging Function and Metabolism by Magnetic Resonance Imaging. Magnetic Resonance Insights. 2017 Jul;10:1–4.
  • Catelani TA, Páscoa RNMJ, Santos JR, Pezza L, Pezza HR, Lima JLFC, et al. A Non-invasive Real-Time Methodology for the Quantification of Antioxidant Properties in Coffee During the Roasting Process Based on Near-Infrared Spectroscopy. Food and Bioprocess Technology. 2017;10(4):630–8.
  • Cavaco MC, Pereira C, Kreutzer B, Gouveia LF, Silva-Lima B, Brito AM, et al. Evading P-glycoprotein mediated-efflux chemoresistance using Solid Lipid Nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics. 2017;110:76–84.
  • Chiari-Andréo BG, Trovatti E, Marto J, De Almeida-Cincotto MGJ, Melero A, Corrêa MA, et al. Guava: Phytochemical composition of a potential source of antioxidants for cosmetic and/or dermatological applications. Brazilian Journal of Pharmaceutical Sciences. 2017;53(2).
  • Custódio-Santos T, Videira M, Brito MA. Brain metastasization of breast cancer. Biochimica et Biophysica Acta - Reviews on Cancer. 2017;1868(1):132–47.
  • dos Santos AG, Bayiha JC, Dufour G, Cataldo D, Evrard B, Silva LC, et al. Changes in membrane biophysical properties induced by the Budesonide/Hydroxypropyl-β-cyclodextrin complex. Biochimica et Biophysica Acta - Biomembranes. 2017;1859(10):1930–40.
  • Dos Santos AG, Marquês JT, Carreira AC, Castro IR, Viana AS, Mingeot-Leclercq M-P, et al. The molecular mechanism of Nystatin action is dependent on the membrane biophysical properties and lipid composition. Physical Chemistry Chemical Physics. 2017;19(44):30078–88.
  • dos Santos CA, Pascoa RNMJ, Sarraguca MC, Porto PALS, Cerdeira AL, Gonzalez-Saiz JM, et al. Merging vibrational spectroscopic data for wine classification according to the geographic origin. Food Research International. 2017;102:504–10.
  • dos Santos CAT, Páscoa RNMJ, Lopes JA. A review on the application of vibrational spectroscopy in the wine industry: From soil to bottle. TrAC - Trends in Analytical Chemistry. 2017;88:100–18.
  • Espadinha M, Dourado J, Lajarin-Cuesta R, Herrera-Arozamena C, Gonçalves LMD, Rodríguez-Franco MI, et al. Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists. ChemMedChem. 2017;12(7):537–45.
  • Fernandes AR, Jesus J, Martins P, Figueiredo S, Rosa D, Martins LMRDRS, et al. Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents. Journal of Controlled Release. 2017;245:52–61.
  • Fernandes B, Maia FM, Paiva AM, Corvo ML, Costa E. Paddle over disk as a dissolution test for orally inhaled drugs: discriminating composite from carrier-based formulations. Journal of Aerosol Medicine And Pulmonary Drug Delivery. 2017;30(4):A6.
  • Fernandes DA, Barros R, Moura C, Costa E, Corvo ML. Impact of spray drying on superoxide dismutase activity in composite systems with optimal aerodynamic performance for dry powder inhalers. Journal of Aerosol Medicine And Pulmonary Drug Delivery. 2017;30(4):A7–8.
  • Fernandes TAP, Aguiar JP, Fernandes AI, Pinto JF. Quantification of theophylline or paracetamol in milk matrices by high-performance liquid chromatography. Journal of Pharmaceutical Analysis. 2017;7(6):401–5.
  • Ferreira M, Rzhepishevska O, Grenho L, Malheiros D, Gonçalves L, Almeida AJ, et al. Levofloxacin-loaded bone cement delivery system: Highly effective against intracellular bacteria and Staphylococcus aureus biofilms. International Journal of Pharmaceutics. 2017;532(1):241–8.
  • Ferreira RC, Neves H, Pinto JF, Lopes CM. Overview on Inhalable Nanocarriers for Respiratory Immunization. Current Pharmaceutical Design. 2017;23(40):6160–81.
  • Figueiredo P, Ferro C, Kemell M, Liu Z, Kiriazis A, Lintinen K, et al. Functionalization of carboxylated lignin nanoparticles for targeted and pH-responsive delivery of anticancer drugs. Nanomedicine. 2017;12(21):2581–96.
  • Freitas AR, Sousa C, Novais C, Silva L, Ramos H, Coque TM, et al. Rapid detection of high-risk Enterococcus faecium clones by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Diagnostic Microbiology and Infectious Disease. 2017;87(4):299–307.
  • Gaspar DP, Faria V, Quintas JP, Almeida AJ. Targeted delivery of lipid nanoparticles by means of surface chemical modification. Current Organic Chemistry. 2017;21(23):2360–75.
  • Gaspar DP, Gaspar MM, Eleutério CV, Grenha A, Blanco M, Gonçalves LMD, et al. Microencapsulated Solid Lipid Nanoparticles as a Hybrid Platform for Pulmonary Antibiotic Delivery. Molecular Pharmaceutics. 2017;14(9):2977–90.
  • Gaspar DP, Serra C, Lino PR, Gonçalves L, Taboada P, Remuñán-López C, et al. Microencapsulated SLN: An innovative strategy for pulmonary protein delivery. International Journal of Pharmaceutics. 2017;516(1–2):231–46.
  • Graça D, Louro H, Santos J, Dias K, Almeida AJ, Gonçalves L, et al. Toxicity screening of a novel poly(methylmethacrylate)-Eudragit nanocarrier on L929 fibroblasts. Toxicology Letters. 2017;276:129–37.
  • Gregorí Valdes BS, Serro AP, Gordo PM, Silva A, Gonçalves L, Salgado A, et al. New Polyurethane Nail Lacquers for the Delivery of Terbinafine: Formulation and Antifungal Activity Evaluation. Journal of Pharmaceutical Sciences. 2017;106(6):1570–7.
  • Gregorí Valdes BS, Vilela CCM, Ascenso A, Bordado JM RH. Topical formulations for onychomycosis: a review. In: Ascenso A, Ribeiro HM, Simões S, editors. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2017. p. 503–53.
  • Jarak I, Carrola J, Barros AS, Gil AM, Pereira ML, Corvo ML, et al. Metabolism modulation in different organs by silver nanoparticles: An NMR metabolomics study of a mouse model. Toxicological Sciences. 2017;159(2):422–35.
  • Lambricht L, Peres C, Florindo H, Préat V, Vandermeulen G. Polymer-Based Nanoparticles as Modern Vaccine Delivery Systems. In: Skwarczynski M, Toth I, editors. Micro and Nanotechnology in Vaccine Development. Oxford: William Andrew Publishing; 2017. p. 185–203.
  • Lana J, Ascenso A. New Trends in Anti-Aging Skin Care. In: Ascenso A, Ribeiro HM, Simões S, editors. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2017. p. 3–41.
  • Manteigas P, Ascenso A. Melatonin: a “guardian” of the genome and cellular integrity for prevention of photocarcinogenesis. In: Ascenso A, Ribeiro HM, Simões S, editors. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2017. p. 43–90.
  • Marcelino P, Marinho HS, Campos MC, Neves AR, Real C, Fontes FS, et al. Therapeutic activity of superoxide dismutase-containing enzymosomes on rat liver ischaemia-reperfusion injury followed by magnetic resonance microscopy. European Journal of Pharmaceutical Sciences. 2017;109:464–71
  • Marques P, Marto J, Gonçalves LM, Pacheco R, Fitas M, Pinto P, et al. Cynara scolymus L.: A promising Mediterranean extract for topical anti-aging prevention. Industrial Crops and Products. 2017;109:699–706
  • Martinho N, Silva LC, Florindo HF, Brocchini S, Barata T, Zloh M. Practical computational toolkits for dendrimers and dendrons structure design. Journal of Computer-Aided Molecular Design. 2017;31(9):817–27
  • Martinho N, Silva LC, Florindo HF, Brocchini S, Zloh M, Barata TS. Rational design of novel, fluorescent, tagged glutamic acid dendrimers with different terminal groups and in silico analysis of their properties. International Journal of Nanomedicine. 2017;12:7053–73
  • Marto J, Jorge I, Almeida A, Ribeiro H. Novel starch-derived topical delivery systems. In: Ascenso A, Ribeiro H, Simões S, editors. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2017. p. 175–216.
  • Marto J, Sangalli C, Capra P, Perugini P, Ascenso A, Gonçalves L, et al. Development and characterization of new and scalable topical formulations containing N-acetyl-d-glucosamine-loaded solid lipid nanoparticles. Drug Development and Industrial Pharmacy. 2017;43(11):1792–800
  • Matos JC, Avelar I, Martins MBF, Gonçalves MC. Greensilica®vectors for smart textiles. Carbohydrate Polymers. 2017;156:268–75
  • Mendes T, Gaspar M, Simões S, Ascenso A. Lipid Vesicles for Skin Delivery: Evolution from first generation. In: Ascenso A, Ribeiro HM, Simões S, editors. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2017. p. 281–321.
  • Mota AH, Rijo P, Molpeceres J, Reis CP. Broad overview of engineering of functional nanosystems for skin delivery. International Journal of Pharmaceutics. 2017;532(2):710–28
  • Mota AH, Silva CO, Nicolai M, Baby A, Palma L, Rijo P, et al. Design and evaluation of novel topical formulation with olive oil as natural functional active. Pharmaceutical Development and Technology. 2017;1–12
  • Moura L, Martinho N, Florindo H, Zloh M. Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy - a computational design approach. FEBS Journal. 2017;284(1, SI):96–7.
  • Moura LIF, Martinho N, Silva LC, Barata TS, Brocchini S, Florindo HF, et al. Poly-glutamic dendrimer-based conjugates for cancer vaccination–a computational design for targeted delivery of antigens. Journal of Drug Targeting. 2017;25(9–10):873–80
  • Neves A, Marto J, Duarte A, Goncalves LM, Pinto P, Figueiredo AC, et al. Characterization of Portuguese Thymbra capitata, Thymus caespititius and Myrtus communis essential oils in topical formulations. Flavour and Fragrance Journal. 2017;32(5):392–402
  • Oliveira GE, Pinto JF. Evaluation of the Potential Use of Laminar Extrudates on Stabilizing Micronized Coumarin Particles by Supercritical Fluids (RESS)—Study of Different RESS Processing Variables and Mode of Operation. AAPS PharmSciTech. 2017;18(7):2792–807
  • Oliveira RF, Teixeira SF, Cabral Marques HM, Teixeira JC. A correlative CFD study between recirculation area and fpm in VHC design. In: Proceedings of the ASME International Mechanical Engineering Congress and Exposition, 2016, Vol 3. New York: Amer Soc Mechanical Engineers; 2017.
  • Oliveira RF, Teixeira SFCF, Cabral-Marques HM, Teixeira JCF. Numerical simulation of salbutamol deposition in vhc devices. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 2017;30(4):A9.
  • Paisana MC, Wahl MA, Pinto JF. An Insight Into the Impact of Polymers on the Hydrate Conversion of Olanzapine Form I in Aqueous Suspensions. Journal of Pharmaceutical Sciences. 2017;106(7):1786–94
  • Paisana MC, Wahl MA, Pinto JF. Effect of polymers in moisture sorption and physical stability of polymorphic olanzapine. European Journal of Pharmaceutical Sciences. 2017;97:257–68
  • Paixão P, Gouveia LF, Silva N, Morais JAG. Evaluation of dissolution profile similarity – Comparison between the f2, the multivariate statistical distance and the f2 bootstrapping methods. European Journal of Pharmaceutics and Biopharmaceutics. 2017;112:67–74
  • Peres C, Matos AI, Conniot J, Sainz V, Zupančič E, Silva JM, et al. Poly(lactic acid)-based particulate systems are promising tools for immune modulation. Acta Biomaterialia. 2017;48:41–57
  • Praça FSG, Marinho HS, Martins MBF, Gaspar R, Corvo ML, Medina WSG. Current aspects of breast cancer therapy and diagnosis based on a nanocarrier approach. In: Ficai A, Grumezescu AM, editors. Nanostructures for Cancer Therapy. Amsterdam: Elsevier; 2017. p. 749–74.
  • Raposo LR, Roma-Rodrigues C, Faísca P, Alves M, Henriques J, Carvalheiro MC, et al. Immortalization and characterization of a new canine mammary tumour cell line FR37-CMT. Veterinary and Comparative Oncology. 2017;15(3):952–67
  • Reis C, Antunes AF, Pereira P, Reis C, Rijo P. Nanosystems for skin delivery: From drugs to cosmetics. Current Drug Metabolism. 2017;18(5):412–25
  • Reis CP, Neufeld RJ, Veiga F, Ribeiro AJ, Neufeld RJ, Veiga F, et al. Preparation of Drug-Loaded Polymeric Nanoparticles. In: Lajos P Balogh, editor. Nanomedicine in Cancer. Singapore: Pan Stanford; 2017. p. 171–214.
  • Resende AP, Silva B, Braz BS, Nunes T, Gonçalves L, Delgado E. Ex vivo permeation of erythropoietin through porcine conjunctiva, cornea, and sclera. Drug Delivery and Translational Research. 2017;7(5):625–31
  • Ribeiro CJA, Nunes RC, Amaral JD, Gonçalves LM, Rodrigues CMP, Moreira R, et al. Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties. European Journal of Medicinal Chemistry. 2017;140:494–509
  • Rodrigues C, Novais Â, Sousa C, Ramos H, Coque TM, Cantón R, et al. Elucidating constraints for differentiation of major human Klebsiella pneumoniae clones using MALDI-TOF MS. European Journal of Clinical Microbiology and Infectious Diseases. 2017;36(2):379–86
  • Roque LV, Dias IS, Cruz N, Rebelo A, Roberto A, Rijo P, et al. Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia. Skin Pharmacology and Physiology. 2017;30(4):197–204
  • Santos FMF, Matos AI, Ventura AE, Gonçalves J, Veiros LF, Florindo HF, et al. Modular Assembly of Reversible Multivalent Cancer-Cell-Targeting Drug Conjugates. Angewandte Chemie - International Edition. 2017;56(32):9346–50
  • Scomparin A, Florindo HF, Tiram G, Ferguson EL, Satchi-Fainaro R. Two-step polymer- and liposome-enzyme prodrug therapies for cancer: PDEPT and PELT concepts and future perspectives. Advanced Drug Delivery Reviews. 2017;118:52–64
  • Silva AF, Sarraguça MC, Fonteyne M, Vercruysse J, De Leersnyder F, Vanhoorne V, et al. Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process. International Journal of Pharmaceutics. 2017;528(1–2):242–52
  • Silva AFT, Sarraguça MC, Ribeiro PR, Santos AO, De Beer T, Lopes JA. Statistical process control of cocrystallization processes: A comparison between OPLS and PLS. International Journal of Pharmaceutics. 2017;520(1–2):29–38
  • Silva AL, Peres C, Conniot J, Matos AI, Moura L, Carreira B, et al. Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation. Seminars In Immunology. 2017;34(C):3–24
  • Silva AS, Quintelas C, Ferreira EC, Lopes JA, Sousa C. Exploiting intrinsic fluorescence spectroscopy to discriminate between Acinetobacter calcoaceticus-Acinetobacter baumannii complex species. RSC Advances. 2017;7(14):8581–8
  • Silva FC, Marto JM, Salgado A, Machado P, Silva AN, Almeida AJ. Nystatin and lidocaine pastilles for the local treatment of oral mucositis. Pharmaceutical Development and Technology. 2017;22(2):266–74
  • Silva MM, Calado R, Marto J, Bettencourt A, Almeida AJ, Gonçalves LMD. Chitosan nanoparticles as a mucoadhesive drug delivery system for ocular administration. Marine Drugs. 2017;15(12)
  • Simoes MG, Alves P, Carvalheiro M, Simoes PN. Stability effect of cholesterol-poly(acrylic acid) in a stimuli-responsive polymer-liposome complex obtained from soybean lecithin for controlled drug delivery. Colloids and Surfaces B-Biointerfaces. 2017;152:103–13
  • Simões S, Carvalheiro M, Gaspar M. Lipid-based nanocarriers for the treatment of infected skin lesions. In: Ascenso A, Ribeiro HM, Simões S, editors. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2017. p. 387–430.
  • Sousa A, Santos F, Gaspar MM, Calado S, Pereira JD, Mendes E, et al. The selective cytotoxicity of new triazene compounds to human melanoma cells. Bioorganic and Medicinal Chemistry. 2017;25(15):3900–10
  • Teixeira dos Santos CA, Páscoa RNMJ, Sarraguça MC, Porto PALS, Cerdeira AL, González-Sáiz JM, et al. Merging vibrational spectroscopic data for wine classification according to the geographic origin. Food Research International. 2017;102:504–10
  • Tomaz AI, de Sousa AD, Santos TC, Soledade Santos M, Luisa Corvo M, Matos C, et al. On the mechanism of action of new active ruthenium anticancer compounds: a model membrane biophysics approach. Journal of Biological Inorganic Chemistry. 2017 Jul;22(1):S179.
  • Varela ARP, Ventura AE, Carreira AC, Fedorov A, Futerman AH, Prieto M, et al. Pathological levels of glucosylceramide change the biophysical properties of artificial and cell membranes†. Physical Chemistry Chemical Physics. 2017;19(1):340–6
  • Viegas C, Faria T, Aranha Caetano L, Carolino E, Viegas S. Pilot study regarding vehicles cabinets and elevator: Neglected workstations in occupational exposure assessment? In: Occupational Safety and Hygiene V - Proceedings of the International Symposium on Occupational Safety and Hygiene, SHO 2017. 2017. p. 283–8.
  • Viegas C, Faria T, Caetano LA, Carolino E, Gomes AQ, Viegas S. Aspergillus spp. prevalence in different Portuguese occupational environments: What is the real scenario in high load settings? Journal of Occupational and Environmental Hygiene. 2017;14(10):771–85
  • Viegas C, Faria T, de Oliveira AC, Caetano LA, Carolino E, Quintal-Gomes A, et al. A new approach to assess occupational exposure to airborne fungal contamination and mycotoxins of forklift drivers in waste sorting facilities. Mycotoxin Research. 2017;33(4):285–95
  • Viegas C, Pacífico C, Faria T, de Oliveira AC, Caetano LA, Carolino E, et al. Fungal contamination in green coffee beans samples: A public health concern. Journal of Toxicology and Environmental Health - Part A: Current Issues. 2017;80(13–15):719–28
  • Viegas C, Santos V, Moreira R, Faria T, Ribeiro E, Aranha Caetano L, et al. Worker’s nasal swab: A tool for occupational exposure assessment to bioburden? In: Occupational Safety and Hygiene V - Proceedings of the International Symposium on Occupational Safety and Hygiene, SHO 2017. 2017. p. 277–82.
  • Viegas S, Caetano LA, Korkalainen M, Faria T, Pacífico C, Carolino E, et al. Cytotoxic and inflammatory potential of air samples from occupational settings with exposure to organic dust. Toxics. 2017;5(1)
  • Vitorino C, Almeida AJ. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) as topical delivery systems for antioxidants. In: Ascenso A, Ribeiro HM, Simões S, editors. Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2017. p. 217–63.
  • Zupancic E, Curato C, Paisana M, Rodrigues C, Porat Z, Viana AS, et al. Rational design of nanoparticles towards targeting antigen-presenting cells and improved T cell priming. Journal of Controlled Release. 2017 Jul;258:182–95.

2016

  • Adeoye O, Figueiredo A, Cabral-Marques H. Cyclodextrins and Skin Disorders: Therapeutic and Cosmetic Applications. In: Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2016. p. 463–502.
  • Arranja A, Gouveia LF, Gener P, Rafael DF, Pereira C, Schwartz Jr. S, et al. Self-assembly PEGylation assists SLN-paclitaxel delivery inducing cancer cell apoptosis upon internalization. International Journal of Pharmaceutics. 2016 Mar;501(1–2):180–9.
  • Ascenso A, Pedrosa T, Pinho S, Pinho F, De Oliveira JMPF, Marques HC, et al. The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes. Oxidative Medicine and Cellular Longevity. 2016;2016.
  • Beloqui A, Solinís MÁ, Rodríguez-Gascón A, Almeida AJ, Préat V. Nanostructured lipid carriers: Promising drug delivery systems for future clinics. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016;12(1):143–61.
  • Bettencourt AF, Feliz M, Sousa C, Gonçalves L, Neves CB. An acrylic reline resin loaded with chlorhexidine: Insights on drug release | Veiculação de clorhexidina em resinas acrílicas de rebasamento: avaliação da libertação do fármaco. Revista Portuguesa de Estomatologia, Medicina Dentaria e Cirurgia Maxilofacial. 2016;57(3):125–31.
  • Caetano LA, Almeida AJ, Gonçalves LMD. Effect of experimental parameters on alginate/chitosan microparticles for BCG encapsulation. Marine Drugs. 2016;14(5).
  • Carrasco MP, Machado M, Gonçalves L, Sharma M, Gut J, Lukens AK, et al. Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites. ChemMedChem. 2016;2194–204.
  • Corvo ML, Marinho H, Martins M. Nanomedicines as a strategy for the therapeutic use of superoxide dismutases. In: Superoxide Dismutase (SOD): Sources, Therapeutic Uses and Health Benefits. New York: NOVA Science Publishers; 2016. p. 135–70.
  • Corvo ML, Mendo AS, Figueiredo S, Gaspar R, Larguinho M, da Silva MFC, et al. Liposomes as Delivery System of a Sn(IV) Complex for Cancer Therapy. Pharmaceutical Research. 2016 Jun;33(6):1351–8.
  • Corvo ML, Mendo AS, Figueiredo S, Gaspar R, Larguinho M, Guedes da Silva MFC, et al. Liposomes as Delivery System of a Sn(IV) Complex for Cancer Therapy. Pharmaceutical Research. 2016;33(6):1351–8.
  • De Matas M, De Beer T, Folestad S, Ketolainen J, Lindén H, Lopes JA, et al. Strategic framework for education and training in Quality by Design (QbD) and process analytical technology (PAT). European Journal of Pharmaceutical Sciences. 2016;90:2–7.
  • Duarte Í, Andrade R, Pinto JF, Temtem M. Green production of cocrystals using a new solvent-free approach by spray congealing. International Journal of Pharmaceutics. 2016;506(1–2):68–78.
  • Duarte Í, Andrade R, Pinto JF, Temtem M. Thermal analysis, X-ray powder diffraction and electron microscopy data related with the production of 1:1 Caffeine:Glutaric Acid cocrystals. Data in Brief. 2016;8:247–50.
  • Duarte Í, Corvo ML, Serôdio P, Vicente J, Pinto JF, Temtem M. Production of nano-solid dispersions using a novel solvent-controlled precipitation process — Benchmarking their in vivo performance with an amorphous micro-sized solid dispersion produced by spray drying. European Journal of Pharmaceutical Sciences. 2016;93:203–14.
  • Durán-Lobato M, Martín-Banderas L, Lopes R, Gonçalves LMD, Fernández-Arévalo M, Almeida AJ. Lipid nanoparticles as an emerging platform for cannabinoid delivery: Physicochemical optimization and biocompatibility. Drug Development and Industrial Pharmacy. 2016;42(2):190–8.
  • Florindo H, Lopes J, Silva L, Corvo M, Martins M, Gaspar R. Regulatory development of Nanotechnology-based vaccines. In: Micro- and Nanotechnology in Vaccine Development. Amsterdam: Elsevier; 2016. p. 393–410.
  • Fonte P, Andrade F, Azevedo C, Pinto J, Seabra V, van de Weert M, et al. Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization. Pharmaceutical Research. 2016;33(11):2777–93.
  • Fonte P, Lino PR, Seabra V, Almeida AJ, Reis S, Sarmento B. Annealing as a tool for the optimization of lyophilization and ensuring of the stability of protein-loaded PLGA nanoparticles. International Journal of Pharmaceutics. 2016;503(1–2):163–73.
  • Gaspar D, Peres C, Florindo H, Almeida A. Mucosal immunization using polyester-based particulate systems. In: Handbook of Polyester Drug Delivery Systems. Singapore: Pan Stanford; 2016. p. 521–61.
  • Gaspar DP, Faria V, Gonçalves LMD, Taboada P, Remuñán-López C, Almeida AJ. Rifabutin-loaded solid lipid nanoparticles for inhaled antitubercular therapy: Physicochemical and in vitro studies. International Journal of Pharmaceutics. 2016;497(1–2):199–209.
  • Gener P, De Sousa Rafael DF, Fernández Y, Ortega JS, Arango D, Abasolo I, et al. Cancer stem cells and personalized cancer nanomedicine. Nanomedicine. 2016;11(3):307–20.
  • Gonçalves LMD, Maestrelli F, Mannelli LC, Ghelardini C, Almeida AJ, Mura P. Development of solid lipid nanoparticles as carriers for improving oral bioavailability of glibenclamide. European Journal of Pharmaceutics and Biopharmaceutics. 2016;102:41–50.
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  • Lopo M, Páscoa RNMJ, Graça AR, Lopes JA. Classification of Vineyard Soils Using Portable and Benchtop Near-Infrared Spectrometers: A Comparative Study. Soil Science Society of America Journal. 2016;80(3):652–61.
  • Magalhães LM, Machado S, Segundo MA, Lopes JA, Páscoa RNMJ. Rapid assessment of bioactive phenolics and methylxanthines in spent coffee grounds by FT-NIR spectroscopy. Talanta. 2016;147:460–7.
  • Marques CF, Matos AC, Ribeiro IAC, Gonçalves LM, Bettencourt A, Ferreira JMF. Insights on the properties of levofloxacin-adsorbed Sr- and Mg-doped calcium phosphate powders. Journal of Materials Science: Materials in Medicine. 2016;27(7).
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  • Marto J, Gouveia LF, Goncalves LM, Gaspar DP, Pinto P, Carvalho FA, et al. A Quality by design (QbD) approach on starch-based nanocapsules: A promising platform for topical drug delivery. Colloids and Surfaces B-Biointerfaces. 2016 Jul;143:177–85.
  • Marto J, Jorge I, Almeida A, Ribeiro H. Novel starch-derived topical delivery systems. In: Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders. Singapore: Pan Stanford; 2016. p. 175–216.
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  • Mograo J, Da Costa CA, Gaspar R, Florindo HF. Modulation of dendritic cells by nanotechnology-based immunotherapeutic strategies. Journal of Biomedical Nanotechnology. 2016;12(3):405–34.
  • Moura L, Martinho N, Barata T, Florindo H, Zloh M. Computational design of a novel poly-glutamic dendrimer-based platform as an anticancer therapeutic approach. FEBS Journal. 2016;283(1, SI):231–2.
  • Oliveira RF, Cabral Marques HM, Machado A V, Teixeira JC, Teixeira SF. VHC performance evaluation at constant flow: 30 L/Min. In: Proceedings of the ASME International Mechanical Engineering Congress And Exposition, 2015, Vol 3. New York: Amer Soc Mechanical Engineers; 2016.
  • Oliveira RF, Teixeira SFCF, Cabral-Marques HM, Teixeira JCF. Space chamber devices in vitro performance evaluation at constant flow. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 2016 Jun;29(3):A3–4.
  • Paisana MC, Müllers KC, Wahl MA, Pinto JF. Production and stabilization of olanzapine nanoparticles by rapid expansion of supercritical solutions (RESS). Journal of Supercritical Fluids. 2016;109:124–33.
  • Paisana MC, Wahl MA, Pinto JF. Role of moisture on the physical stability of polymorphic olanzapine. International Journal of Pharmaceutics. 2016;509(1–2):135–48.
  • Paixão P, Gouveia L, Morais J, Silva N. Correlation between cell- and tissue-based in vitro models for drug permeability screening with in vivo situation. In: Concepts and Models for Drug Permeability Studies: Cell and Tissue based In Vitro Culture Models. Amsterdam: Elsevier; 2016. p. 357–71.
  • Peres C, Matos AI, Viana AS, Graca L, Preat V, Florindo HF. Nanoparticle-based cancer vaccine to target dendritic cells and the tumor microenvironment. FEBS Journal. 2016;283(1, SI):36–7.
  • Pinto JT, Brachkova MI, Fernandes AI, Pinto JF. Evaluation of the ability of powdered milk to produce minitablets containing paracetamol for the paediatric population. Chemical Engineering Research and Design. 2016;110:171–82.
  • Páscoa RNMJ, Lopo M, Teixeira dos Santos CA, Graça AR, Lopes JA. Exploratory study on vineyards soil mapping by visible/near-infrared spectroscopy of grapevine leaves. Computers and Electronics in Agriculture. 2016;127:15–25.
  • Ribeiro CJA, Espadinha M, Machado M, Gut J, Gonçalves LM, Rosenthal PJ, et al. Novel squaramides with in vitro liver stage antiplasmodial activity. Bioorganic and Medicinal Chemistry. 2016;24(8):1786–92.
  • Ruivo EFP, Gonçalves LM, Carvalho LAR, Guedes RC, Hofbauer S, Brito JA, et al. Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes. ChemMedChem. 2016;2037–42.
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  • Salústio P, Miguel M, Cabral-Marques H. Molecular (Cyclodextrin) Encapsulation of Volatiles and Essential Oils. In: Handbook of Encapsulation and Controlled Release. Boca Raton: CRC Press (Taylor & Francis); 2016. p. 867–906.
  • Santos CA, Pascoa RNMJ, Porto PALS, Cerdeira AL, Lopes JA. Application of Fourier-transform infrared spectroscopy for the determination of chloride and sulfate in wines. LWT-Food Science and Technology. 2016;67:181–6.
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  • Santos JR, Lopo M, Rangel AOSS, Lopes JA. Exploiting near infrared spectroscopy as an analytical tool for on-line monitoring of acidity during coffee roasting. Food Control. 2016;60:408–15.
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