- Course Objectives
- Target audience
- Course Structure
- Program and Evaluation
The advanced specialization course on Medicinal Chemistry and Chemical Biology Strategies for Drug Discovery is intended to frame the training of students who have been admitted to the PhD program in Pharmacy. It is a highly flexible programme covering a wide range of courses taught by chemists, pharmacists, biologists and industrial medicinal chemists. It provides a strong foundation in core chemistry, supplemented by specialist knowledge of medicinal chemistry and chemical biology.
PhD students at the FFUL.
The Course will also be open to other participants, namely professionals in the related areas, master’s and doctoral students, or doctoral researchers working in related areas.
This course will run from July 03, 2023 to July 07, 2023. It has a total of 25 h of training
Total of ECTS: 6 ECTS.
The training hours are distributed as follows:
- Theoretical Hours: 16
- Practical hours: 0
- Laboratory Hours: 9
- Tutorial Hours: 0
The course will take place over 5 days, from 09:15h to 18:00h, at the FFUL.
Program and Evaluation
|July 3||July 4||July 5||July 6||July 7|
|Medicinal Chemistry and drug discovery
|Chemical tools for target identification
|Computational tools and Artificial Intelligence-powered drug discovery||New therapeutic modalities
|Hands-on session using LC-MS: working with proteins
|Opening Lecture (Luc van Hijte, Symeres, NL)||Introduction to light-induced processes (Uwe Pischel, Huelva, ES)
|Challenges and opportunities for AI in drug discovery
(Tiago Rodrigues, iMed FFUL)
|Strategies for targeted protein degradation: PROTACS
|Hands-on session using LC-MS: working with proteins|
|Therapeutic targets and emerging drugs for COVID19
(Ana Martinez, CSIC, ES)
|Opto-chemical tools for target modulation (Pau Gorostiza (Barcelona))||Structure-based drug design (Rita Guedes, iMed FFUL)||Strategies for targeted protein degradation: molecular glues TBC||Hands-on session using LC-MS: working with proteins|
|11:30||Coffee break||Coffee break||Coffee break||Coffee break||Coffee break|
|12:00||Medicinal chemistry for antimalarial drug discovery
(Rui Moreira, iMed FFUL)
|Chemical probes for cell imaging (David Ng, Mainz, DE)||Hand-on session on silico strategies||Bioconjugates in drug discovery (Pedro Góis, iMed FFUL)||Closing Lecture (industry speaker)|
|13:00||Lunch||Lunch||Lunch||Lunch||Closing & Lunch|
|14:30||Targeting necroptosis and ferroptosis in drug discovery
|Hand-on session using LC-MS: drug metabolism and ADMET||Free afternoon||Hand-on session on silico strategies||
|Designing enzyme inhibitors targeting serine hydrolases TBC||Hand-on session using LC-MS: drug metabolism and ADMET||Free afternoon||Integrating predictive models and drug discovery data for MedChem 2.0 (Teodoro Laino IBM)|
|16:30||Coffee break||Coffee break||Coffee break|
|17:00||Targeting Mycobacterium tuberculosis for TB drug discovery TBC||Hand-on session using LC-MS: drug metabolism and ADMET||Free afternoon||Hand-on session on silico strategies|
Applications and Enrollment: by june 29, 2023
Course Start and Completion Date: july 03 to july 07, 2023
Bachelor’s or Master’s degree.
Selection and seriation criteria:
Order of entry of applications.
- Minimum number of students to function: 10
- Maximum number of trainees to run: 20
Note: FFUL doctoral students who wish to take the course as part of their 1st year curricular component are exempt from paying the registration fee.
School Insurance: 2.03€
By application of paragraph e) of point 2 of Article 42 of the University of Lisbon’s Statutes, and taking into account the terms for the attribution of PRR funding under the “Impulso Adultos” program, the Organic Unit responsible for the coordination of each course may award academic performance prizes.
Access to the FenixEdu Platform:
- If you have never been a student at FFULisboa you must pre-register on the FenixEdu Platform.
- If you are a former student of FFULisboa and have already had an account campus@ulisboa or @edu.ulisboa.pt you should access the FenixEdu Platform and authenticate yourself with your account data. If you have lost access to your account, you can recover your password in the ULisboa users area.
- If you are a former student of FFULisboa and have never had an account campus@ulisboa or @edu.ulisboa.pt you must send an email to firstname.lastname@example.org indicating your full name and ID document number.
Access the FenixEdu Platform.
- On the tab “Candidate”, choose the type of application: “Advanced Training Courses”, select the course “Medicinal Chemistry and Chemical Biology Strategies for Drug Discovery – General Public”.
- Fill out the online form and attach all documents in digital format.
- Select the “Submit” option.
For information regarding the organization of the course, please contact the Academic Services: email@example.com
For scientific information regarding the teaching of the course, please contact the Course Coordination.