Radioisotope Unit

The University of Lisbon Faculty of Pharmacy Radioisotope Unit (beta) is a research and teaching facility licensed by the Directorate General of Health. It was built from the ground up specifically for this purpose. It is located in Building F of the Lumiar Campus. It consists of 5 rooms / labs designed and equipped as a research and teaching laboratory. Includes areas for labelling proteins, macromolecules and other low molecular weight compounds, by chemical modification. Its proximity to the vivarium facilitates in vivo studies, such as pharmacokinetics, biodistribution and metabolic studies.

This laboratory has strict rules imposed by the requirements to improve staff safety while handling radioactive samples. All new users should complete a radiation safety training course.

SERVICES

The Radioisotope Unit offers its facilities (rooms and equipment) for experimental procedures (in vivo and in vitro) that involve the manipulation of radioactive material.

PRICES

Prices for services will be subject to prior agreement and depend on the procedure to be performed, its duration and the number of users involved.

Please contact us for a quote.

WORKS CARRIED OUT

This unit has enabled a diverse range of work in many of the scientific areas at FFUL and iMed.Ulisboa and in collaboration with other national research institutions, as can be seen in the following list of selected articles:

Corvo ML, Martins MBF, Francisco AP, Morais JG, Cruz MEM. Liposomal formulations of Cu,Zn-superoxide dismutase: physico-chemical characterization and activity assessment in an inflammation model. J Control Release. 1997;43(1):1-8.

Lopes RM, Corvo ML, Eleuterio CV, Carvalheiro MC, Scoulica E, Cruz ME. Formulation of oryzalin (ORZ) liposomes: In vitro studies and in vivo fate. Eur J Pharm Biopharm. 2012;82(2):281-290.

Moura V, Lacerda M, Figueiredo P, Corvo ML, Cruz MEM, Soares R, de Lima MCP, Simoes S, Moreira JN. Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer. Breast Cancer Res Treat. 2012;133(1):61-73

CONTACT DETAILS

Contact person: Maria Luísa Corvo

Address – Faculty of Pharmacy, University of Lisbon,

Lumiar Campus, Estrada do Paço do Lumiar, 22, Edifício F, R/C, 1649-038 Lisbon, Portugal

Tel.: +351 217 500 763

Email: lcorvo@ff.ulisboa.pt

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