Research Grants

R&D projects as Principal Investigator and Member of the Team

R&D projects as Principal Investigator

"Dementia associated with HIV infection - study of infectious and inflammatory mechanisms mediated by extracellular vesicles". Financed by Gilead Sciences (Gilead Génese Program), at the Host-Pathogen Interaction Unit, iMed.Ulisboa, Faculty of Pharmacy, University of Lisbon; starting date: February 2020. Coordinator: Prof. Doutor José Miguel Azevedo-Pereira.

Role of the ectossomes in the dissemination of HIV infection in central nervous system and their role in the pathogenesis of HIV-associated dementia”. Financed by Gilead Sciences (Gilead Génese Program), at the Host-Pathogen Interaction Unit, iMed.Ulisboa, Faculty of Pharmacy, University of Lisbon; starting date: February 2017. Coordinator: Prof. Doutor José Miguel Azevedo-Pereira.  

HIV-2 interaction with macrophages and dendritic cells: implications in the reduced pathogenicity of HIV-2” (VIH/SAU/0006/2011). Financed by Fundação para a Ciência e Tecnologia, at the Host-Pathogen Interaction Unit, iMed.Ulisboa, Faculty of Pharmacy, University of Lisbon; starting date: April 2014. Coordinator: Prof. Doutor José Miguel Azevedo-Pereira.

VIKIA HIV1/2 - evaluation of rapid tests for early detection of anti-HIV-1/HIV-2 antibodies”. I&D project financed by bioMérieux Portugal, at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, since 2008 until 2010. Coordinator: Prof. Doutor José Miguel Azevedo-Pereira.

Interaction between HIV-2 and target cell - Identification of new coreceptors used by CCR5- and CXCR4-independent strains and its role in HIV-2 pathogenesis / Interacção do HIV-2 com a célula alvo - Identificação de novos co-receptores usados por estirpes CCR5- e CXCR-independentes e a sua importância na patogénese do HIV-2” (POCI/SAU-IMI/55726/2004). Financed by Fundação para a Ciência e Tecnologia, at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, since January 2006 until July 2010. Coordinator: Prof. Doutor José Miguel Azevedo-Pereira.

Viral/sera library”. Financed by Coordenação Nacional da Infecção VIH/SIDA (CNIVS 28-1.7.3/2004), Merck Sharp & Dhome Portugal, Associação Nacional das Farmácias and Gilead Sciences, at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, since June 2004. Coordinator: Prof. Doutor José Miguel Azevedo-Pereira and Prof. Doutora Maria Odette Santos-Ferreira.

"Characterization and in vivo Evolution of Primary HIV-2 Strains That Do Not Use CCR5 or CXCR4" (POCTI/ESP/39987/2001). Financed by Fundação para a Ciência e Tecnologia, at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, since March 2002 until December 2005. Coordinator: Prof. Doutor José Miguel Azevedo-Pereira.

R&D projects as Member of the Team

Manipulation of lysosomal cathepsins and their inhibitors cystatins in human macrophages as a host directed therapeutic strategy for tuberculosis and co-infection with HIV". Financed by Fundação para a Ciência e Tecnologia, at Host-Pathogen Interactions Unit, Research Institute for Medicines, iMed-ULisboa, Faculdade de Farmácia da Universidade de Lisboa, since 2018. Coordinator: Profª. Doutora Elsa Anes.

Compatibilidade funcional do complexo de replicação como determinante de virulência nos vírus influenza”. Financed by Fundação para a Ciência e Tecnologia, at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, since January 2012. Coordinator: Profª. Doutora Helena Rebelo de Andrade.

"O Papel dos Vírus Monocitotrópicos na Patogénese da Infecção pelo HIV", Financed by Comissão Nacional de Luta contra a SIDA, at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, between 1996 and 1999. Coordinator: Prof. Doutor José Moniz-Pereira.

Molecular understanding of membrane events leading to retrovirus entry into host cells and viral propagation”. Financed by European Community Commission (Directorate General for Science Research and Development), at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, between 1989 and 1991. Coordinator: Prof. J.-M. Ruysschaert; National coordinator: Prof. Doutora Maria Odette Santos-Ferreira.

Seroprevalência e biologia molecular do HIV-1 e HIV-2 em seis províncias da República Popular de Angola”. Financed by Junta Nacional de Investigação Científica (JNICT 89.679), at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, between 1987 and 1989. Coordinator: Prof. Doutora Maria Odette Santos-Ferreira.

Prevalence of HIV-1 and HIV-2 positivity in a well-characterized (social-economically) population”. Financed by Junta Nacional de Investigação Científica (JNICT 88.98), at the Unidade dos Retrovírus e Infecções Associadas, Faculty of Pharmacy, University of Lisbon, between 1987 and 1989. Coordinator: Prof. Doutora Maria Odette Santos-Ferreira.

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