This course will focus on a molecular level understanding of organic chemistry. The course will provide the basic knowledge of organic chemistry by attending typical reactions of functional groups from a mechanistic perspective, current aspects of carbanion, carbocation, radical, and carbene chemistry, stereochemistry, organic functional group transformation, basic concepts of strategy in designing syntheses of organic compounds.
The course will be an instructional model to teaching the essential knowledge in organic chemistry emphasizing the real interdisciplinary with biochemistry and biology.
A comprehensive understanding of the organic chemical basis equips the master students with the ability to answer questions related to drug development and
drug action, and explore the same concepts in laboratory practice.
Introduction to Organic Chemistry. Molecular Representation.
Stereochemistry of organic molecules.
Reactions involving nucleophilic aditton and nucleophilic substitution in the carbonyl group: aldehydes and ketones reactivity.
Nucleophilic substitution in the saturated carbon: mechanistic aspects of the haloalkanes and alcohols reactivity.
Electrophilic addition reactions to alkenes and alkynes. Oxidation reactions.
Enol reactivity: Carbon-carbon ligation. β-dicarbonylic compounds.
Radicalar reactions in alkanes
Aromatic compounds: substitution reactions with aromatic properties maintenance.
Laboratory experimentation – Drug synthesis