Master in Laboratory Medicine

Hematology II



Learning outcomes

This unit aims to teach and to transfer competence to the student in order to:

  • To identify pathological conditions and differentiate malignant from non­malignant hematological disease .
  • Understand the importance of pre­analytical phase in the obtained
  • Learn to interpret correctly cytograms and histograms of normal and pathological bloods and correlate the data with the morphological
  • Get interpret haematological parameters, depending on the patient’s medical history and correlate them with those from other analytical laboratory areas
  • Understand the principle of the different techniques used and learn to adapt them to the study of the diseases and , also , the importance of knowledge of the mechanisms underlying the disease, in order to develop accurate diagnoses and develop new, more specific molecular targets .
  • Be cautious in providing doubtful results and get a sense of the urgency of getting some data.


Theoretical education :

  • Bonne Marrow : Biopsies and aspirates
  • Anemias and poliglobulias . Hemochromatosis. Porphyrias
  • Quantitative, qualitative, nonmalignant and malignant leukocyte diseases
  • Chromosomal abnormalities in tumors . Cytogenetic analysis techniques (classical, FISH M­FISH/SKY , RT­ PCR and microarray )
  • Tumors of haematopoietic and lymphoid tissue . FAB and WHO Classifications
  • Acute leukemias.Myeloproliferative and myelodysplastic neoplasms,
  • Hodgkin’s and non­Hodgkin’s Myeloma.
  • Pathology of Congenital and adquired diseases.
  • Hematopoietic transplantation
  • Pharmacotherapy of hematological

Laboratory Teaching :

  • Analysis of blood samples , bone marrow and lymph node biopsy malignancies .
  • Execution of differencial leukocyte counts
  • Cytograms and histograms of non­malignant and malignant diseases .
  • Cytochemical staining and functional study of macrophages
  • Discussion of clinical laboratory cases .