Master in Biopharmaceutical Sciences

Neuropathology and Neuropharmacology

ECTS

4

Learning outcomes

To know the main events that may cause the onset of neurodegenerative diseases and changes related to aging;
To understand the main cellular and molecular mechanisms associated with neurodegeneration and disease biomarkers;
To identify therapeutic targets and meet possible strategies for its modulation by either natural products or by drugs;
To understand the approaches used for computational drug design.

Syllabus

Neurological impairment and neurodegeneration;
Neurodegeneration mechanisms: role of oxidative stress, excitotoxicity and cell death pathways;
Susceptibility of various cell types to neurodegeneration induced by various insults;
Neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis;
Neuromodulation by pharmacological agents and neuroprotection through natural products;
Brain tumors and valuation of glioma cell susceptibility to a drug;
Computational drug design.

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