Integrated Master in Pharmaceutical Sciences

Pharmaceutical Biotechnology

ECTS

6

Learning outcomes

Students will acquire skills on the identification and understanding the subject of Pharmaceutical Biotechnology and Bioengineering, the important role of biotechnology medicines and biological therapies. They should know and develop skills on different bioproduction technologies, sources from the production itself, to quality control in bioprocess and final product and the application of European and American Legislation. They should acquire skills in the areas of biomaterials and application in immobilization of enzymes and cells, on animal cell technology, cell and gene therapies. They should also gain the knowledge bases required for new developments in this area (eg biosimilars, novel therapies) and market biotech companies.
Students should develop self-study, research and critical thinking, communication and interconnection of concepts with various parts of the knowledge to be acquired.

Syllabus

The Pharmaceutical Biotechnology is divided in three modules: the first provides an introduction to biotechnology, to biocatalysts (e.g. enzymes and cells), to cell growth and nutrition, and kinetic, energy and environmental factors on the growth and production of metabolites, to cell culture in batch, continuous and semi-continuous. This module also includes biomaterials and immobilization of biocatalysts.
In the second is presented the stages of production, the various types of bioreactors and operating conditions, the production of microbial cells and animals, metabolites and recombinant proteins, to the biotechnology medicines, according to European and American Legislation. The separation and purification processes are also topics studied.
These issues are complemented in the last module with examples of biotech drugs, antibiotics, recombinant therapeutic proteins (eg antibodies, erythropoietin, vaccines) to market biosimilar and biotechnology companies.

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