Integrated Master in Pharmaceutical Sciences

Organic Chemistry I

ECTS

7

Learning outcomes

Organic Chemistry I begins the acquisition of competences on organic chemistry that have impact on the understanding of drug action and analysis. The main goals of this course are to train the students with the skills and knowledge on the structure, reactivity and structural elucidation of organic compounds that are required to address the challenges involved in drug synthesis and drug design.

Specifically, this course is designed to give emphasis to the study of structure-reactivity, and it is intended that the students learn the structure, the synthesis and the reactivity of some functional groups. Another goal is to provide students the learning of fundamentals of Nuclear Magnetic Resonance and Infrared spectroscopy and their application in structural characterization. It is also intended to emphasize the importance of Organic Chemistry in the understanding of certain biological phenomena at the molecular level.

And other goal is to introduce students to laboratorial practice.

Syllabus

  • Infrared spectroscopy
  • Proton Nuclear Magnetic Resonance spectroscopy (1H-NMR)
  • Carbon 13 Nuclear Magnetic Resonance spectroscopy (13C-NMR)
  • Alkanes and cycloalkanes. Radicalar reactions
  • Alkyl halides. Substitution reactions (SN1 and SN2)
  • Preparation via elimination reactions (E1 and E2)
  • Addition reactions of alkenes. Electrophilic and radical additions
  • Alkynes
  • Alcohols and ethers
  • Sulfur analogues of alcohols and ethers
  • Dienes and systems with delocalized pi electrons

The laboratorial classes are divided in two modules. The first one is directed towards unit operations and the second focuses on organic synthesis.

Share