The study of immunology will enable the student to gain a broad foundation base and build upon that base for understanding the defense mechanisms of the human body. Such foundation will be germane either for advanced courses or for any student actively involved in the pharmaceutical sciences.
As a result of successfully completing this course, the student will be able to do the following:
A. Demonstrate a comprehensive and practical understanding of basic immunological principles involved in research and clinical/applied science.
B. Differentiate between innate and adaptive immunity.
C. Explain the mechanisms and differences between primary and secondary responses and their relevance to immunizations.
D. Identify the role of antigen presenting cells, lymphocytes, and phagocytic cells in immune responses.
E. Differentiate between humoral and cell mediated immunity.
F. Discuss current immunology news and issues.
The Immunology course is designed to provide a foundation in the basic concepts and terminology of immunology. It commences with the important components (cells, tissues, antibodies, immunoglobulins) involved in host defense against infectious agents. Introductory lectures serve to describe and differentiate between natural defense (innate) mechanisms and adaptive immunity mediated by functional B and T lymphocytes and their products. Subsequently, cellular interactions, especially the differentiation of helper T cell subsets and the production of relevant cytokines, will be described. This will include the mechanisms of T cell activation and regulation. Finally, clinical immunology will be discussed. Topics covered include: autoimmunity and autoimmune diseases; hypersensitivity reactions including atopic disorders and asthma; mechanisms of transplant rejection; and immunodeficiency disorders.