Integrated Master in Pharmaceutical Sciences

General Chemistry

ECTS

6

Learning outcomes

The General Chemistry course is a basilar course intended to introduce students to the basic concepts of chemistry concerning atomic and molecular structure, chemical bonding and reactivity, in organic and inorganic structures. This course is an indispensable pedagogical tool for the consolidation and development of knowledge and skills that enables students to an appropriate progression in chemistry-related areas.

Students are intended to be able to:
- organize and relate concepts;
- solve problems related to the topics covered, on the basis of acquired knowledge;
- interpret results critically;
- adapt the acquired knowledge to new situations.

Syllabus

Atomic structure and atomic models. Schrodinger equation. Chemical bonding: ionic bond and covalent bond; molecular orbital theory and valence bond theory; molecular geometry and hybridization of atomic orbitals. Chemical kinetics. Kinetics of radioactive decay; biological effects of radiation. Organic molecules. Lewis structures. Molecular dipole moment. Formal charges. Newman and Fisher projections. Resonance. Main functional groups. Nomenclature rules. Stereochemistry. Main conformations of cycloalkanes. Isomerism. Constitutional isomers and stereoisomers. Cis-trans isomerism. (E)-(Z) system. Enantiomerism. Chirality. Optical activity. (R)-(S) system. Meso compounds. Stereoisomerism in cyclic compounds. Relative and absolute configurations. D and L series. Introduction to transition-metal chemistry. Role of transition-metal in macromolecules. Alkaline and alkaline earths. Oxygen and its compounds: properties and biological influence.

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