Integrated Master in Pharmaceutical Sciences

Bacteriology

ECTS

7

Learning outcomes

Upon completion of this course, students should be able to:
A. Knowledge and Understanding
Have a broad knowledge of the main concepts and basic principles of Bacterial structure, physiology, growth control, Genetics and Diversity of Bacteria. Understand the relevance of bacterial role in Health, as agents of human diseases, as agents of pharmaceutical and food spoilage, in Industrial microbiology as producers of medical productsand in biotechnology in the production of therapeutic proteins and vaccine
B. General Skills
Acquire skills in microscopic techniques for direct examination of bacteria. And be able to isolate and quantify bacteria. To know the basic techniques of bacterial identification and performing susceptibility tests to antimicrobial agents.

Syllabus

The Microbial world. Relevant aspects of the history of Microbiology
Microscope in Microbiology
Functional anatomy of bacterial cell
Nutrition and growth: culture media, isolation of cultures, growth curve
Physical and Chemical methods of control of Microbial growth
Bacterial Metabolism: Catabolism and anabolismo. Physiology: Coping with environmental changes. Communication and cooperation between bacterial populations.
Quorum-sensing. Formation of organized communities
Bacterial genetics and evolution. Mechanisms of genetic modification and exchange
Microbial genetic engineering applications
Principles of Bacterial classification: Phenotypic and phylogenetic classifications
Interactions between bacteria and man. The normal human microbiota and its importance
Virulence factors and bacterial toxins
Antibiotics: Mechanisms of action and bacterial resistance. Quantification of antimicrobial activity
Relevant bacterial groups in human health and pharmaceutical industry

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